Acne
Virilization in a woman is the most common reaction associated with anabolic steroids, especially when higher doses are used. Acne occurs frequently in all age groups and both sexes. Nausea, vomiting, diarrhea, fluid and electrolyte imbalances (the same as for the androgens, discussed previously), testicular atrophy, jaundice, anorexia, and muscle cramps may also be seen. Fluid retention, not deficiency, is a common side effectof anabolic steroid use. Sedation and hypotension are not adverse reactions to this hormone.
Which condition is an indication for a primary health care provider to prescribe Danazol for a female patient?
Danazol is a drug used to manage endometriosis, a condition in which endometrial cells grow on tissue outside the uterus, including the fallopian tubes and ovaries.
Which category of drugs is contraindicated with the concurrent use of the phosphodiesterase inhibitor sildenafil Viagra )?
PDE5 inhibitors decrease cGMP degradation. The concomitant use of these agents can cause a significant increase in cGMP accumulation, resulting in a synergistic reduction in BP. Therefore, the use of PDE5 inhibitors with any form of organic nitrates is contraindicated.
Which pharmacologic class is used to describe testosterone drugs?
Class Summary
All testosterone preparations are regulated as Schedule III controlled substances according to the Anabolic Steroids Control Act.
What is the mechanism of action of sildenafil?
Sildenafil is a phosphodiesterase inhibitor used for the treatment of erectile dysfunction. In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) 11,12,13,14,15,16,8,9.