A nurse is contributing to the plan of care for a school-age child who has acute poststreptococcal

This NCLEX review will discuss acute glomerulonephritis (poststreptococcal).

As a nursing student, you must be familiar with acute glomerulonephritis and how to care for patients who are experiencing this condition.

These type of questions may be found on NCLEX and definitely on nursing lecture exams.

Don’t forget to take the acute glomerulonephritis quiz.

You will learn the following from this NCLEX review:

• Definition of acute glomerulonephritis
• Causes
• Pathophysiology
• Signs and Symptoms
• Nursing Interventions

Acute Glomerulonephritis NCLEX Review

What is acute glomerulonephritis (poststreptococcal)? It is the inflammation of the filtering structure of the nephron (what is the filtering structure of the nephron? Glomerulus) that causes permeability to protein and red blood cells due to previous strep infection. Therefore, protein and red blood cells will be present in the urine.

Facts about Acute Glomerulonephritis

• It tends to present 14 days after a strep infection of the throat or skin (impetigo).
• It mainly affects the pediatric population ages 2-10.
• It is not caused from the strep bacteria attacking the glomerulus butthe immune system’s response to the bacteria by creating antigen-antibody complexes, which inflames the glomerulus. This is why you see it AFTER a strep infection
• Glomerulonephritis is an umbrella term for various types of kidney disorders where there is injury to the glomerulus and they can be nephritic or nephrotic.
  • Poststreptococcal glomerulonephritis is a type of NEPHRITIC SYNDROME meaning there is the leakage of BOTH red blood cells and a mild amount of protein from the inflamed glomerulus.
    • Contrasting: Nephrotic Syndrome (which we will discuss in the next lecture) is an inflamed glomerulus that is leaking massive amount of proteins into the filtrate (NOT red blood cells)

Reviewing the Basics about Nephron Anatomy

Role of Glomerulus (this is what is damaged in acute glomerulonephritis): it filters the blood and removes ions, water, waste EXCEPT proteins and bloods cells (they are too big to pass through)

What is happening in Poststreptococcal Glomerulonephritis?

The glomerulus becomes inflamed due to a recent infection from a group of bacteria called streptococcus.

This causes major problems:

Hematuria: patient will present with cola colored or tea colored urine

Proteinuria (mild): this  can lead to low amounts of protein found in the blood

What happens when there is a low amount of protein the blood? Swelling in the interstitial tissue…hence EDEMA. The swelling mainly presents in the face/eyes and will be mild.

 Why mild swelling? Within the capillaries are a protein called albumin that regulates oncotic pressure. Albumin creates oncotic pressure by controlling how much water stays within the capillaries. Capillaries have

Fluid overload: at risk for heart failure, renal failure, and respiratory distress due to congestion of fluid in lungs (retaining salt and water), hypertension

Decrease glomerular filtration rate (GFR): What is GFR? It is the flow rate of filtered fluids through the kidneys, specifically the glomerulus.

• Why does the GFR decrease? Inflammation of the glomerulus leads to other immune cells to present at the site of inflammation. The site becomes congested. Therefore, the glomerulus isn’t able to filter the blood normally. Due to this, waste in the blood build-ups (remember the kidneys are NOT filtering normally) and this increases the blood urea nitrogen (BUN) and creatinine levels.

Low Urine Output: Oliguria (watch potassium levels…hyperkalemia…the potassium will start to build-up in the blood because the kidney’s filtration rate has decreased)

Hypertension: WHY? decreased filtration rate of the kidneys, increased blood volume, and retaining sodium

• At risk for hypertensive encephalopathy due to prolonged/untreated high blood pressure which can affect the brain…watch for neuro changes, headaches, and seizures

Signs and Symptoms of Acute Glomerulonephritis

“Had Strep”

Hypertension

ASO antistreptolysin titer positive (test used to diagnose strep infections)

Decreased GFR (low urine output)

Swelling in face/eyes (edema)…mild

Tea-colored urine (cola colored)…from hematuria

Recent strep infection

Elevated BUN and creatinine

Proteinuria (mild)

Nursing Interventions for Acute Glomerulonephritis

Monitor fluid status VERY closely: patient may be prescribed diuretics (if renal function is normal)

Daily weights (weight gain is the earliest sign of fluid retention): use same standing scale every day. Try to avoid bed scale if possible…standing scales are the best.

Strict calculation of intake and output (at risk for low urinary output if renal failure presents)

Since the disorder mainly affects the pediatric population remember these patients should void 1mL/kg/hr.

How much should a patient who is 30 lbs void? 13.6 mL/hr

• If Oliguric (low urinary output) watch for hyperkalemia WHY? When the GFR is decreased, potassium is not excreted properly which leads to hyperkalemia
• Assess color of urine…is the urine starting to look normal?

Assess swelling status in face/around the eyes and extremities (mainly in the face/around the eyes and it is worst in the mornings)

Monitor lung sounds for crackles…signs of pulmonary edema

Monitor BUN and Creatinine levels ….renal failure

Monitor vital signs ESPECIALLY blood pressure (may experience hypertension…it can become severely elevated and this can lead to hypertensive encephalopathy)

Bedrest until recovered: due to hypertension

Sodium restriction along with fluid restriction diet (helps with edema and hypertension) and if oliguria is present restrict potassium-rich foods until recovered

Administering diuretics and antihypertensives or antibiotics to treat presenting strep infection (if needed…not always ordered) per MD order

Education: importance of seeking treatment for infections of the skin or throat…strep infection can reoccur

More NCLEX Reviews

References:

1. “Glomerular Diseases | NIDDK”. National Institute of Diabetes and Digestive and Kidney Diseases. N.p., 2014. Web. 5 June 2017.
2. “Group A Strep | Post-Streptococcal Glomerulonephritis | | PSGN | GAS | CDC”. Cdc.gov. N.p., 2016. Web. 5 June 2017.