A nurse is preparing to administer warfarin to a client who has a new onset of atrial fibrillation

Paresthesia

Rationale:
The nurse should apply the safety and risk-reduction priority-setting framework, which assigns priority to the factor or situation posing the greatest safety risk to the client. When there are several risks to client safety, the one posing the greatest threat is the highest priority. The nurse should use Maslow's hierarchy of needs, the ABS priority-setting framework, and/or nursing knowledge to identify which risk poses the greatest threat to the client.

The greatest risk to this client is neurotoxicity. Vincristine, a cell-cycle specific chemotherapy agent, interrupts cellular reproduction at mitosis and can cause neurotoxicity. An early finding with neurotoxicity is PARESTHESIA (numbing) of the peripheral extremities. As neurotoxicity progresses, the client can develop autonomic and central nervous system dysfunction. The nurse should report paresthesia immediately, as the provider might change the dosage or type of therapy

Which of the following laboratory values should the nurse monitor for a therapeutic effect of warfarin?

International normalized ratio (INR) Rationale: The INR is used to monitor clients who are taking warfarin.

What is the most important information for the nurse to include when teaching a client about metronidazole?

IMPORTANT WARNING: Metronidazole can cause cancer in laboratory animals. Talk to your doctor about the risks and benefits of taking this medication.

For which reasons would the nurse monitor older adults taking heparin more closely for bleeding?

Heparin requires close monitoring because of its narrow therapeutic index, increased risk for bleeding, and potential for heparin-induced thrombocytopenia (HIT).

Which medication will the nurse administer to a client who experienced a thrombotic stroke two days ago?

tPA (tissue plasminogen activator) It can stop a stroke by breaking up the blood clot. It must be given as soon as possible and within 4½ hours after stroke symptoms start.