Topic Resources Infants whose weight is > the 90th percentile for gestational age are classified as large for gestational age. Macrosomia is birthweight > 4000 g in a term infant. The predominant cause is maternal diabetes. Complications include birth trauma, hypoglycemia, hyperviscosity, and
hyperbilirubinemia. Fenton T, Kim J: A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants. BMC Pediatrics 13:59, 2013. doi: 10.1186/1471-2431-13-59; used with permission. Available at
www.biomedcentral.com. Fenton T, Kim J: A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants.
BMC Pediatrics 13:59, 2013. doi: 10.1186/1471-2431-13-59; used with permission. Available at www.biomedcentral.com. Rare causes of macrosomia are Beckwith-Wiedemann syndrome (characterized by macrosomia, omphalocele, macroglossia, and hypoglycemia) and Sotos, Marshall, and Weaver syndromes. Perinatal asphyxia Other complications occur when weight is > 4000 g. There is a proportional increase in morbidity and mortality due to the following: IDMs are at risk of
Congenital anomalies are more likely in IDMs because maternal hyperglycemia at the time of organogenesis is detrimental. Specific anomalies include
Persistently elevated insulin levels can also lead to increased deposition of glycogen and fat into cardiomyocytes. This deposition can cause transient hypertrophic cardiomyopathy, predominantly of the septum.
Click here for Patient Education Copyright © 2022 Merck & Co., Inc., Rahway, NJ, USA and its affiliates. All rights reserved. What are LGA babies at risk for?The most common problems of LGA infants (hypoglycemia, birth injuries, and lung problems) typically resolve over a few days with no long-term consequences. As adults, LGA girls have an increased risk of having an LGA infant. All LGA infants are at risk of obesity and may have an increased risk of heart disease.
Why are LGA infants at risk for hypoglycemia?All the extra sugar and the extra insulin that is made can lead to fast growth and deposits of fat. This means a larger baby. It also means a risk for low blood sugar right after birth. At that point, the mother's supply is no longer there, but the baby's insulin levels stay high.
What does it mean if my baby is large for gestational age?Large for gestational age is a term used to describe babies who are born weighing more than the usual amount for the number of weeks of pregnancy.
What are potential risks for SGA and LGA neonates?They are, however, at increased risk of the following problems:. Perinatal asphyxia. ... . Meconium aspiration. ... . Low blood sugar (glucose) levels ( hypoglycemia. ... . Excess red blood cells ( polycythemia. ... . Difficulty regulating body temperature.. |